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Clinical evaluation of the effectiveness and the skin tolerance of SilveRpès
versus a placebo on patients with labial herpes

Study conducted by Groupe Dermscan, a center of clinical experimentation chartered by the French Ministry of Health and by AFSSAPS (French Health Products Safety Agency), ISO 9001/2008 certified.

Objectives of the trial

  • Evaluation of the clinical effectiveness based on the specific parameters of a cold sore: dryness, erythema, edema, vesicles, re-epithelialization, lesion size, scabs and exudates;
  • Clinical evaluation of the tolerance to the products under study;
  • Subjective evaluation of their sensory characteristics, their effectiveness, their tolerance to a later application;

Conclusions about the effectiveness and the tolerance of SilveRpès

  • SilveRpès  results in a faster dissolution of herpes symptoms rather than produced by the placebo on the following parameters: cyst,  re-epithelialization, size and scab;
  • SilveRpès  demonstrated a good tolerance on the skin, the placebo having demonstrated a very good tolerance on the skin;
  • SilveRpès was appreciated by the volunteers for its organoleptic characteristics and its effectiveness; most volunteers wish to continue the use of SilveRpès  and would be likely to buy it at the end of the test.


  • Double-blind study versus a placebo;
  • Kinetic: D0-D1-D2-D3-D4-D5-D6-D7-D8-D9 & D10;
  • Zone: labial zone presenting the cold sore and/or the symptoms.

Related documents

  1. Clinical results of SilveRpès on cysts
  2. Clinical results of SilveRpès on re-epithelialization
  3. Clinical results of SilveRpès  on the size of the lesion
  4. Clinical results of SilveRpès on the scabs